The purpose of this book is to propose a new incentive to stimulate economic and social development in Africa. This incentive is to implement and promote a prize similar to the framework of the Nobel Prize that would promulgate science and reward the scientists that have contributed to the development of the African continent. Incidentally, it will advocate for the need of having a higher level of education in Africa and a highly skilled human capital to lead the prospective regional economic growth. Created in 1901 by Swedish Businessman and chemist, Alfred Nobel; the Nobel Prize is the most coveted prize in the world. It rewards intellectual outstanding contributions to the advancement of the knowledge in a particular field of study which has taking humanity into a positive direction. Its influence and prestige have deeply impacted the world and enhanced science as a vehicle to improve the quest for knowledge as well as to ameliorate the economic condition of societies. This book seeks to expound how the “African Nobel Prize” could significantly contribute to the stimulation for the economic and social development in Africa.